FDA cleared AliveCor’s suite of next-generation interpretive ECG algorithms for KardiaMobile and 6L devices, which now add determination of premature ventricular contractions, supraventricular ectopy, and wide QRS as well as improved sensitivity and specificity of normal and atrial fibrillation determinations, the company announced.
Boston Scientific recalled all stock of its Lotus Edge transcatheter aortic valve devices and retired the entire platform globally due to problems with the delivery system.
Myocardial injury in severe COVID-19 was actually less than seen with acute respiratory distress syndrome from other causes after accounting for age, comorbidities, and other factors. (Circulation)
Myocarditis from COVID-19 turned up in 1.4% to 7.2% of autopsies in a meta-analysis — much less than suggested by the most prominent series. (Cardiovascular Pathology)
Four cases of catastrophic, large arterial thrombosis were reported in young and asymptomatic post-COVID patients at a median 78 days after seroconversion in a series from Singapore. (Journal of Thrombosis and Thrombolysis)
Cytokine-driven endothelial dysfunction appeared to be behind post-COVID vascular complications in a study reported without peer review on the preprint server medRxiv.
JACC: Basic to Translational Science has a primer for cardiologists on RNA-based COVID-19 vaccines.
Notable among the losses of late in the field of cardiology were interventional cardiologist Anthony Gershlick, MD, and clinical electrophysiologist John J. Gallagher, MD.
Cynicism plus hostility was linked to poorer cardiovascular reactivity to stress in experiments reported in Psychophysiology.
Type 2 myocardial infarction often wasn’t evaluated by a cardiologist during admission and typically didn’t get outpatient cardiology follow-up afterward even at Massachusetts General Hospital. (Circulation: Cardiovascular Quality and Outcomes)
The American Heart Association and the American College of Cardiology updated guidelines for managing hypertrophic cardiomyopathy (HCM), encouraging shared decision-making. (Circulation)
Mavacamten improved cardiac remodeling in obstructive HCM without changes in fibrosis or contractile function in an EXPLORER-HCM cardiac magnetic resonance substudy reported in Circulation.
The Society of Cardiovascular Computed Tomography and North American Society of Cardiovascular Imaging released expert consensus recommendations on coronary CT imaging of atherosclerotic plaque. (Journal of Cardiovascular Computed Tomography)
The FDA cleared the Indigo Aspiration System Lightning 12 to treat pulmonary embolism, Penumbra announced.
More time sedentary was linked to more heart failure hospitalizations in older women. (Circulation: Heart Failure)
Pooled post-hoc data from the phase III ORION trials of novel inclisiran showed consistency of LDL-lowering effects across age and gender in atherosclerotic cardiovascular disease or heterozygous familial hypercholesterolemia, Novartis announced.